Hello Gopal,
Please refer to section Wily Introscope setup for BOE 4.0 of this wiki:
Managed System Setup of BOE 4.0 system in Solman 7.1 - SAP Solution Manager Setup - SCN Wiki
You may also found interesting
Maintenance of Product in the System Landscape - SAP Solution Manager Setup - SCN Wiki
https://service.sap.com/sap/support/notes/1722874
https://service.sap.com/sap/support/notes/1357901
Best Regards.
Luis Roel